Getting Started¶

PIPIT¶

What is PIPIT?¶

PIPIT is a simple package to design shuffled protein sequences to interupt function. Specifically, by specifying the protein region to shuffle as well as the size of sequence ‘blocks’ to shuffle, you can quickly generate variants that will allow you to rapidly interrogate the function of specific protein regions by changing the order of amino acids in that region.

How do you use PIPIT?¶

PIPIT can be used within Python or from the terminal.

Installation:¶

From PyPi, just use

$ pip install idptools-pipit

To clone the GitHub repository and gain the ability to modify a local copy of the code, run

$ git clone https://github.com/idptools/PIPIT.git
$ cd PIPIT
$ pip install .

This will install PIPIT locally.